Chemistry deals with phenomena that affect nearly every aspect of our lives and environment. A liberal education in this scientific and technological age should include some exposure to the theories, laws, applications, and potential of this science.

The chemistry curriculum is sufficiently flexible to allow students with career interests in areas such as the health professions, law, business, and education to design a major program suitable to their goals. Students interested in careers in chemistry or biochemistry will find sufficient chemistry electives to provide a strong background for graduate work, industry, or other positions requiring an in-depth foundation in chemistry. A major in biological chemistry has been developed in conjunction with the biology department. See separate listing under Biological Chemistry for more details. The department and its curriculum are approved by the American Chemical Society.

Major Requirements. All students majoring in chemistry are required to meet the following minimum course requirements: Chemistry 107A or Chemistry/Environmental Studies 107B; Chemistry 108A or Chemistry/Environmental Studies 108B; Chemistry 203; 206; 212; 215; 217–218; either Chemistry 331 or 332; either Chemistry 223 or any 300-level chemistry course (except Chemistry 331 and 332); and at least one course selected from the following: Computer Science 101; Mathematics 205; Mathematics 206; Physics 301; or Psychology 218. Further course and unit selections depend upon the goals and interests of the student. All students preparing for graduate study or for a position in the chemical industry should include in their programs Chemistry 223, 316, and any other advanced courses in their specific area of interest. It should be noted that courses in mathematics and physics are prerequisites for some of the advanced courses in chemistry. A written thesis is required of all majors. This may be either a laboratory or library thesis. Students doing a laboratory thesis may register for Chemistry 457, 458, or both, while students doing a library project may register for Chemistry 457 or 458. Students in the Honors Program must register for 457 and 458. All senior majors must participate in the departments seminar program. Each major is required to deliver two research presentations during the senior year.

Pass/Fail Grading Option. Pass/fail grading may not be elected for courses applied toward the major.

General Education. The following sets are available: 107A–108A, 107A–108B, 107B–108A, 107B–108B, 107A–125, 107B–125. Chemistry 125, 132, s21, s23, s24, and s28 may serve as an option for the third course. The quantitative requirement may be satisfied through any chemistry course or unit except Chemistry 132, s21, or s28.

Courses
107A. Atomic and Molecular Structure. Fundamental concepts underlying the structure and behavior of matter are developed. Major topics include states of matter, atomic structure, periodicity, and bonding. This course, or its equivalent, is a prerequisite for all advanced courses in chemistry. Laboratory: three hours per week. Enrollment limited to 60 per section. Not open to students who have received credit for Chemistry 107. M. Côté, P. Schlax.

107B. Chemical Structure and Its Importance in the Environment. Fundamentals of atomic and molecular structure are developed with particular attention to how they relate to substances of interest in the environment. Periodicity, bonding, states of matter, and intermolecular forces are covered. The laboratory involves a semester-long group investigation of a topic of environmental significance. This course is the same as Environmental Studies 107B. Enrollment limited to 60 per section. Not open to students who have received credit for Chemistry 107. T. Wenzel.

108A. Chemical Reactivity. A continuation of Chemistry 107A. Major topics include thermodynamics, kinetics, equilibrium, acid/base behavior, and electrochemistry. Laboratory: three hours per week. Prerequisite(s): Chemistry 107A or Chemistry/Environmental Studies 107B. Enrollment limited to 60 per section. Not open to students who have received credit for Chemistry 108. T. Lawson, P. Schlax.

108B. Chemical Reactivity in Environmental Systems. A continuation of Chemistry/ Environmental Studies 107B. Major topics include thermodynamics, kinetics, equilibrium, acid/base chemistry, and electrochemistry. Biogeochemical cycles provide examples for course topics. The laboratory analyzes the chemistry of marine environments. Prerequisite(s): Chemistry 107A or Chemistry/Environmental Studies 107B. This course is the same as Environmental Studies 108B. Enrollment limited to 60 per section. Not open to students who have received credit for Chemistry 108. R. Austin.

125. Bioenergetics. Living organisms require nutrients extracted from the environment to support the chemical reactions necessary for all life processes including development, growth, motion, and reproduction. Maintaining the chemical reactions that allow the web of life to continue to exist on earth demands a continuous input of energy. This course examines the flow of energy from the sun into the biosphere through plants and into animals, with a focus on humans. Through the use of a combination of learning techniques, including research and oral presentations, problem solving, and group discussions, the chemistry behind this energy flow is explored, as are the ways in which energy is used by living organisms. May not be applied toward the chemistry or biological chemistry major. Recommended background: high school chemistry. Enrollment limited to 30. T. Lawson.

132. Women in Chemistry. Women continue to be under-represented in chemistry. Furthermore, important discoveries made by women are often omitted from the chemistry curriculum. Topics addressed in this course include the important scientific contributions of women chemists; the barriers that have inhibited and factors that have promoted the participation of women in chemistry, including aspects of balancing family and career; the extent to which practices and descriptive language in chemistry are inscribed with gender; and feminist critiques of science, particularly as they apply to chemistry. Enrollment limited to 50. T. Wenzel.

203. Statistical Thermodynamics. Major topics include statistical mechanics and thermodynamics. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B, Mathematics 105 and 106. Prerequisite(s) or Corequisite(s): Physics 107. M. Côté.

206. Quantum Chemistry. Major topics include quantum mechanics, atomic and molecular structure, and spectroscopy. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B, Physics 107, Mathematics 105 and 106. Corequisite(s): Physics 108. Recommended background: Physics 301. M. Côté.

212. Separation Science. A study of some of the most universally used methods and techniques of chemical separation. Both theory and applications are covered. Topics include chemical equilibrium, liquid-liquid extraction, gas and liquid chromatography, and electrophoresis. Laboratory: three hours per week. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B. T. Wenzel.

215. Descriptive Inorganic Chemistry. A study of the wide-ranging aspects of inorganic chemistry. The use of periodic trends and fundamental principles of inorganic chemistry to systematize the descriptive chemistry of the elements is explored. Topics include reaction mechanisms in inorganic chemistry, ligand field theory, and solid state chemistry. Applications of inorganic chemistry to biochemistry, environmental chemistry, and geochemistry are also considered. Laboratory: three hours per week. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B. R. Austin.

217. Organic Chemistry I. An introduction to organic chemistry. Topics include bonding, structure, and nomenclature; reactions of alkanes, alkenes, alkylhalides, alkynes, and aromatics; and spectroscopic methods. Laboratory: three hours per week. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B. J. Koviach.

218. Organic Chemistry II. A continuation of Chemistry 217. The reactions of organic halides, alcohols, phenols, ethers, carbonyl compounds, and organic nitrogen compounds are studied from both a mechanistic and a synthetic point of view. Laboratory: three hours per week. Prerequisite(s): Chemistry 217. J. Koviach.

220. Biophysical Chemistry. This course is an overview of physical chemical principles and techniques used in understanding the properties, interactions, and functions of biological molecules. Thermodynamic, kinetic, and statistical mechanical principles are applied to understanding macromolecular assembly processes (i.e., assembly of viruses or ribosomes) and macromolecular interactions involved in gene expression and regulation, DNA replication, and other biological processes. Techniques used in studying protein folding, RNA folding, and enzyme kinetics are presented. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B, Physics 107, Mathematics 105 and 106. Recommended background: Biology s42 and Chemistry 321. P. Schlax.

223. Analytical Spectroscopy and Electrochemistry. Spectroscopic and electrochemical methods employed in chemical analysis are discussed. Topics include ultraviolet, visible, infrared, and atomic spectroscopy; and potentiometric and voltametric methods of analysis. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B. T. Wenzel.

306. Electrons in Solids. A study of the electronic properties of solid materials. Subjects include the application of quantum theory to simple models of crystalline solids, the chemical and optical properties of solids, the impact of surfaces on material behavior, and quantum confinement. Prerequisite(s): Chemistry 206. M. Côté.

313. Spectroscopic Determination of Molecular Structure. In this course the utilization of nuclear magnetic resonance (NMR) and mass spectral data for structural analysis is developed. Particular attention is given to the interpretation of proton, carbon-13, and two-dimensional NMR spectra, and to the interpretation of fragmentation patterns in electron-impact mass spectrometry. Theoretical and instrumental aspects of modern NMR spectroscopy and mass spectrometry are covered. Prerequisite(s): Chemistry 218. T. Wenzel.

316. Bonding and Symmetry in Inorganic Chemistry. A study of electronic structure in inorganic chemistry focusing both on theoretical models and spectroscopic characterizations. Primary emphasis is placed on the application of group theory to the elucidation of electronic structure. Prerequisite(s): Chemistry 206. R. Austin.

321. Biological Chemistry I. An introduction to biologically important molecules and macromolecular assemblies. Topics discussed include the structure and chemistry of proteins; the mechanisms and kinetics of enzyme catalyzed reactions; and the structure, chemistry, and functions of carbohydrates, lipids, nucleic acids, and biological membranes. Laboratory: three hours per week. Prerequisite(s): Chemistry 218. Recommended background: Biology s42. T. Lawson.

322. Biological Chemistry II. A survey of the major metabolic processes in living cells. Topics discussed include protein synthesis, DNA replication and gene expression, the global organization of metabolic pathways, carbohydrate and fatty acid metabolism, biological oxidation, reduction and energy production, and the metabolism of nitrogen-containing compounds. Special attention is given to the mechanisms by which metabolic processes are regulated. Laboratory: three hours per week. Prerequisite(s): Chemistry 321. T. Lawson.

325. Organic Synthesis. A study of important organic reactions with emphasis on structure, stereochemistry, mechanism, and synthesis. Prerequisite(s): Chemistry 218. Staff.

326. Advanced Organic Chemistry. Lectures and discussions on various aspects of theoretical organic chemistry related to the structure of organic molecules and reactive intermediates. Topics include molecular orbital theory, orbital symmetry, thermodynamics, conformational analysis, and kinetics. Prerequisite(s): Chemistry 218. Recommended background: Chemistry 203. Staff.

327. Topics in Macromolecular Chemistry. Macromolecular chemistry is a broad subject encompassing the synthesis, characterization, properties, and uses of polymers. Current areas of research in macromolecular chemistry, techniques used to characterize macromolecules, and unique physical properties of macromolecules are introduced. Students explore topics including synthesis of biodegradable plastics, structure and functions of catalytic RNA, structural characterization of polymers, characterization or uses of semiconducting polymers, dendrimer synthesis, mechanisms of molecular evolution, harnessing DNA as a microprocessor or micromotor. Prerequisite(s): Chemistry 218. P. Schlax.

331. Thermodynamics and Kinetics Laboratory. The application of thermodynamics and kinetics to the experimental study of chemical systems. Students measure changes in thermodynamic quantities associated with chemical, biochemical, and physical processes, and interpret their results. Both standard and more recently developed experimental techniques are employed. In addition, the kinetics of chemical reactions are observed and then modelled both analytically and through computer-based numerical techniques. Prerequisite(s) or Corequisite(s): Chemistry 203 or 220. M. Côté, P. Schlax.

332. Spectroscopy Laboratory. The use of spectroscopic methods to probe atomic and molecular structure, and to identify, characterize, and quantify chemical species is examined. Theoretical and experimental aspects of several techniques including nuclear magnetic resonance, infrared spectroscopy, and UV-visible spectroscopy are covered. Prerequisite(s): Chemistry 206. M. Côté, T. Wenzel.

360. Independent Study. Students, in consultation with a faculty advisor, individually design and plan a course of study or research not offered in the curriculum. Course work includes a reflective component, evaluation, and completion of an agreed-upon product. Sponsorship by a faculty member in the program/department, a course prospectus, and permission of the chair is required. Students may register for no more than one independent study per semester. Staff.

457, 458. Senior Research and Seminar. A laboratory or library research study in an area of interest under the supervision of a member of the department. Each senior major delivers two presentations on his or her research. Students register for Chemistry 457 in the fall semester and for Chemistry 458 in the winter semester. Majors writing an honors thesis register for both Chemistry 457 and 458. Staff.

Short Term Units
s21. Biotechnology: Life Science for Citizens. A nonscientist's introduction to the science of the biotechnology revolution. Topics include the basic biology and chemistry of cells, the biochemistry of gene expression, the development and applications of recombinant DNA and related technologies, and the structure and functioning of the biotechnology research establishment in the United States. Weekly laboratory exercises include a DNA cloning project. Not open to majors in chemistry, biological chemistry, or biology. Enrollment limited to 18. T. Lawson, P. Schlax.

s22. Chemistry for the Curious Citizen. A nonscientist's introduction to chemistry. Collaborative laboratories introduce important concepts through observation and experimentation. Emphasis is on real-life applications such as treatment of anemia or iron overload, design of a fireproof safe, detection and remediation of contaminants in the wastewater, effects of increasing atmospheric carbon dioxide, and other problems. Recommended background: high school chemistry course. Not open to science majors and to students who have received credit for Chemistry 107 and 108. Enrollment limited to 20. Staff.

s23. Science Meets Art: Loudspeaker Design and Construction. Hands-on experience in the science and art of designing, building, and testing audio loudspeakers serves as a practical introduction to the concepts of waves and resonance. Students purchase parts and materials to build loudspeakers of their own design, which they then keep. Students with either technical or nontechnical backgrounds are equally welcome. Enrollment limited to 8. M. Côté.

s27. Nucleic Acids. This unit provides an overview of the structure and function of DNA and RNA. Major topics include techniques for discerning structure, DNA structure, RNA structure, RNA catalysis, and interactions of nucleic acids with ligands. The unit involves critical reading and discussion of primary literature in a seminar format. Prerequisite(s): Chemistry 218. Recommended background: Biology s42 and Chemistry 321. Enrollment limited to 20. P. Schlax.

s28. Digital Signals. Digitized signals are playing an increasing role in scientific measurements, telecommunications, and consumer electronics. While it is often claimed that "the future is digital," there are trade-offs and limitations associated with any signal processing technique. This unit exposes students to the realities of analog and digital data acquisition, basic forms of signal processing, and their application to scientific measurements and to consumer electronics, including audio. Hands-on experience is gained by constructing simple electronic circuits and creating signal acquisition and manipulation software. No previous electronics or computer programming experience is necessary. Recommended background: Mathematics 105. This unit is the same as Physics s28. Open to first-year students. Enrollment limited to 15. M. Côté.

s32. Practical Genomics and Bioinformatics. Genomics is the emerging science of studying genes and gene function as dynamic, coordinated systems. Bioinformatics refers to the development of methods for storing, retrieving, analyzing, and integrating biological molecule sequence data. These new branches of science have become both possible and necessary because of the recent and extremely rapid accumulation of DNA sequence data that has resulted from technological advances in biochemistry and molecular biology. This unit explores the methods by which this data has been, and continues to be, collected, including cloning techniques, sequencing procedures, and methods for monitoring gene expression. What this information means and how it can be analyzed is examined through the use of internet-accessible sequence databases and software tools. The theoretical becomes the practical through a project to sequence and analyze the expression of a gene from a marine organism. Students live and work for two weeks at the Mount Desert Island Biological Laboratory. Recommended background: Biology 131 or Biology s42. Enrollment is limited to 16. T. Lawson. New unit beginning Short Term 2002.

s34. Chemical Pollutants: Science and Policy. On what basis are chemicals in the environment regulated? How are acceptable levels of exposure determined? This unit examines how these sorts of public policy decisions are made by studying a few chemicals as examples. Topics covered include chemical structures and toxicity, the notion of "risk" and who defines it, and the role of scientific information in the legal process. Prerequisite(s): Chemistry 108A or Chemistry/Environmental Studies 108B. This unit is the same as Environmental Studies s34. Open to first-year students. Enrollment limited to 30. R. Austin.

s50. Independent Study. Students, in consultation with a faculty advisor, individually design and plan a course of study or research not offered in the curriculum. Course work includes a reflective component, evaluation, and completion of an agreed-upon product. Sponsorship by a faculty member in the program/department, a course prospectus, and permission of the chair is required. Students may register for no more than one independent study during a Short Term. Staff.

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Last Modified: 3/4/02 by mkm