A & P - Notes
Chapter 17.

STUDY GUIDE and VOCABULARY
BLOOD
  • Blood composition and functions:       Know the overall composition of blood and the various types of
          blood cells (names, general appearance, role in maintaining health).
  • Hematopoiesis:       Know, in general terms, which blood cells develop in myeloid tissue and which develop in lymphoid
          tissue;   you DO NOT need to know the names of all the immature stages.
  • Hemostasis:       Know, in general terms, how blood clots.
  • Blood antigens and blood groups:       Know how blood groups depend upon the ABO and Rh antigen systems.
  • Blood development:       Know how and why blood cells need to be replenished, including the role of stem cells.
  • Blood disorders:       Know the causes and symptoms of the more common disorders affecting blood.

  • VOCABULARY TO KNOW:
            THIS LIST IS UNDER DEVELOPMENT AND MAY EXPAND
            Blood:   a connective tissue containing liquid matrix (plasma) and formed elements including blood cells.
            Plasma:   the liquid matrix of blood or lymph.
            Formed elements:   cells or cell fragments present in blood or lymph.
            Red blood cells (erythrocytes):   round red blood cells packed with oxygen-carrying hemoglobin, and lacking a nucleus when mature.
            White blood cells (leucocytes):   pale-colored blood cells (of several kinds) without hemoglobin.
            Granular leucocytes (granulocytes):   leucocytes containing granules distinguished by their staining properties.
            Neutrophils:   the most common leucocytes, phagocytic cells with a multi-lobed nucleus and granules staining with neutral dyes.
            Basophils:   leucocytes with granules that stain with basic dyes.
            Eosinophils:   leucocytes that stain with acidic dyes such as eosin.
            Lymphocytes:   non-granular leucocytes essential in immune functions.
            Monocytes:   large non-granular leucocytes that become tissue macrophage cells (phagocytic).
            Megakaryocytes:   large cell from which platelets are derived.
            Platelets:   cellular fragments essential in blood clotting.
            Clotting:   deposition of insoluble fibrin, a process that turns blood into solid connective tissue.
            Serum:   the watery fluid remaining after blood clots; blood serum minus its proteins.
            Lymphoid tissue:   tissue (in spleen, thymus, etc.) in which nongranular leucocytes mature.
            Myeloid tissue:   tissue (in bone marrow) in which granular leucocytes mature.
            Hematopoiesis:   the process of blood cell formation in myeloid and lymphoid tissues.
            Erythroblast:   an immature erythrocyte before its nucleus is extruded.
            Antigen:   any molecule provoking an immune response.
            Antibody:   a soluble protein molecule that binds to a specific antigen.
            Anemia:   reduction in the oxygen-carrying capacity of blood (for any of several reasons, including the following).
            Sickle-cell anemia:   anemia caused by a gene mutation in hemoglobin that results in deformed erythrocytes.   (The allele, common in many African populations, confers protection against malaria.)
            Thalassemia:   anemia (often mild) caused by a gene mutation that results in a shortened hemoglobin chain.   (Thalassemia alleles, more common in Mediterranean populations, also confer protection against malaria.)
            Malaria:   blood infection caused by a parasitic protist (Plasmodium falciparum and related species), causing anemia, fever, weakness, and frequently death.
            Hemophilia:   lack of clotting ability in the blood.
            Polycythemia vera:   very rare cancer in which red blood cells are excessively produced.
            Leukemia:   any cancer of leucocytes (several kinds).

 
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rev. June, 2015