HUMAN VARIATION


ABO BLOOD GROUPS


BLOOD TYPE Antigens Antibodies     Can give blood to: Can receive blood from: Possible genotypes:
  A   A   anti-B   A or AB   A or O   AA, Ao
  B   B   anti-A   B or AB   B or O   BB, Bo
  AB   A and B   neither   AB only   any type   AB
  O   neither  anti-A, anti-B    any type   O only   oo





Human Var.   Question 1













Genotype HbAHbA HbAHbS HbSHbS
Relative Fitness 0.85 1.00 0.
Why? Susceptible
to malaria
Resistant
to malaria
Sickle-cell anemia
(usually fatal)




Human Var.   Question 2





Skin pigmentation (melanin, etc.)
Skin cancer   vs.   Vitamin D





Human Var.   Question 3